These are questions asking what a person did or will do at a certain place and at a certain point in time. Usually the time word is placed before the place noun.
あなたは きのう しんじゅくで なにを しましたか。
What did you do in Shinjuku yesterday?
あなたは あした ぎんざで なにを しますか。
What are you going to do in Ginza tomorrow?